This is one of the most common questions we are asked. Even though there is no direct answer as every situation is different, there are numerous factors that need to be considered when deciding on the best sampler. Usually poor sampling results are a direct result of not choosing the correct tool.

The reason for sampling is critical when selecting the correct sampler. Sampling could be for goods-in checking, retention samples, microbiological testing or final quality analysis. Different applications require completely different devices.

The type of material being sampled is one of the most important considerations. Powders, granules, liquids and viscous materials all behave differently and require specialist equipment.

For example, poor flowing powders often require different samplers compared to free flowing powders. Choosing the wrong device can lead to inaccurate or inconsistent sampling results.

The sampling environment must also be considered carefully. Factors include headroom, confined spaces, cleaning facilities and machine accessibility.

The material construction of the sampler is critical. You should consider chemical compatibility, corrosion resistance and contact time with the sample material.

• Will the material react with the sampler?
• Is the material corrosive?
• Does the sampler require FDA or EU compliance?
• Is a sterile or disposable option required?

If reusable equipment is selected, it should be easy to dismantle and clean. Many customers now prefer SteriWare® disposable samplers as they completely eliminate cleaning requirements.

Surface finish is especially important for powders and pharmaceutical applications. Mirror polished and electropolished finishes improve cleanability and reduce material adhesion.

Different applications may require different levels of certification and traceability documentation. Examples include:

• Material certification
• FDA / EU compliance
• Sterilisation certificates
• Surface finish certificates
• Batch-specific documentation

If powders or liquids are flammable or capable of generating static electricity, suitable ATEX or grounded equipment should be considered. A full risk assessment is always recommended.

Correct sample handling, storage and transfer are essential for obtaining accurate and repeatable results. Minimising contamination and ensuring suitable containers are used are key parts of good sampling practice.

A full assessment of the sampling process and environment should always be carried out. This includes ventilation, PPE, lighting, training and overall safety procedures.

• Adequate ventilation
• Correct PPE
• Proper lighting
• Sufficient working space
• Operator training